| Pcs | Single Vial, 3-Pack, 6-Pack, Pack of 10 |
|---|---|
| Strength | 10ml, 3ml |
Reconstitution Solution
Price range: $7.00 through $87.00
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VERIFICATION
How to read this report
Reconstitution Solution, in structural terms.
- Sequence
- Not applicable. Reconstitution Solution is a solvent, not a peptide, and has no amino acid sequence.
- Molecular formula
- C₇H₈O (benzyl alcohol); the bulk component is water, H₂O
- Molecular weight
- Benzyl alcohol: approximately 108.14 g/mol
- CAS number
- 100-51-6 (benzyl alcohol)
- Structure type
- Reagent
- Primary molecular target
- No molecular target. Benzyl alcohol acts by partitioning into microbial cell membranes and disrupting membrane integrity, a physicochemical mechanism rather than receptor binding. The solution is a diluent and is not itself under investigation as an active compound.
- Physical form
- Solution
- PubChem CID
- 244
Reconstitution Solution is water containing benzyl alcohol at a nominal 0.9% as a bacteriostatic agent. It is a two-component solution rather than a single compound. Benzyl alcohol (C7H8O, about 108.14 g/mol) is an aromatic alcohol that inhibits microbial growth, which is why it is used as a preservative in laboratory diluents. The figures for formula, weight and CAS on this page describe benzyl alcohol, the active component.
Where Reconstitution Solution appears in the literature.
- Published and routine laboratory use of bacteriostatic diluents includes:
- Reconstitution of lyophilized peptide and protein preparations
- Preparation of stock solutions for multi-day assay sequences
- Preservative efficacy testing against USP compendial organisms
- Excipient compatibility and peptide aggregation studies
- Sorption and container-closure interaction studies
- Research use only. Not for human or animal consumption.
- Systems reported in the preservative literature include:
- Compendial challenge organism panels used in preservative efficacy testing
- Peptide and protein formulations under accelerated stability conditions
- Polymeric and elastomeric container-closure systems for sorption study
- Cell-free analytical systems for content determination
- Assay formats applied to this material include:
- HPLC with UV detection for benzyl alcohol content and purity
- LC-MS for component identity confirmation
- Limulus Amebocyte Lysate endotoxin assay under USP <85>
- Visual inspection for clarity and particulate matter
- Gas chromatography for residual solvent profiling
- Endpoints reported for this material include:
- Benzyl alcohol concentration as a percentage
- Chromatographic purity
- Endotoxin concentration against assay sensitivity
- Appearance and clarity
- Research use only. Not for human or animal consumption.
What has been studied, and in what systems.
Benzyl alcohol is one of the most studied preservatives in formulation science, because the property that inhibits microbial growth can also affect the stability of dissolved proteins and peptides.
Studies of a reconstituted lyophilized protein formulation found that benzyl alcohol increased protein aggregation, and that the effect depended on concentration and storage conditions (Roy et al., 2005). Related work traced the aggregation to partial unfolding of the protein in the presence of benzyl alcohol (Zhang et al., 2004).
Benzyl alcohol can also be lost from solution by sorption into flexible tubing and other polymeric materials, which changes its effective concentration (Bahal and Romansky, 2002). These studies are why the measured benzyl alcohol content of each lot is reported on its certificate.
These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.
Zhang Y et al., 2004. Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution. J Pharm Sci. PMID 15514986. https://pubmed.ncbi.nlm.nih.gov/15514986/
Roy S et al., 2005. Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations. J Pharm Sci. PMID 15614819. https://pubmed.ncbi.nlm.nih.gov/15614819/
Bahal SM, Romansky JM, 2002. Sorption of benzoic acid, sorbic acid, benzyl alcohol, and benzalkonium chloride by flexible tubing. Pharm Dev Technol. PMID 11852696. https://pubmed.ncbi.nlm.nih.gov/11852696/
About this compound and its batch data.
What is Reconstitution Solution?
Reconstitution Solution is water containing benzyl alcohol at a nominal 0.9% as a bacteriostatic agent. Benzyl alcohol is CAS 100-51-6, C7H8O, 108.14 g/mol. Astramide supplies it in 3 mL vials as a laboratory diluent for reconstituting lyophilized material. It is not intended for human or animal consumption, clinical use, or therapeutic application.
What is Reconstitution Solution used for in the laboratory?
It is used to bring lyophilized research materials into solution for laboratory work. The benzyl alcohol inhibits microbial growth, so a prepared solution can be kept and sampled over a working period under refrigeration rather than being discarded after a single use. Research use only.
What purity does the current Reconstitution Solution lot reach?
Lot White Cap returned 99.98% chromatographic purity by HPLC-UV, tested by Freedom Diagnostics under accession 2608270451 and reported 30 August 2026. Identity was confirmed by LC-MS as benzyl alcohol. The full certificate is published on this page and every figure shown here is taken from it.
How much benzyl alcohol is in the vial?
The laboratory measured 0.95% benzyl alcohol against a nominal 0.9% specification. Astramide publishes the measured figure rather than the nominal figure. Note that this is a concentration, not a net weight: unlike a lyophilized peptide, a solution is characterised by component percentage rather than milligrams per vial.
How is Astramide's Reconstitution Solution tested?
Testing is performed by Freedom Diagnostics. Lot White Cap was analysed by four methods: identity by LC-MS, chromatographic purity by HPLC-UV, benzyl alcohol content by HPLC-UV, and endotoxin by Limulus Amebocyte Lysate under USP 85. Both endotoxin replicates passed at an assay sensitivity of 0.05 EU/mL or below.
How should Reconstitution Solution be stored?
Store at controlled room temperature, protected from light, with the closure intact. Storage conditions printed on the vial label take precedence. Handling is for qualified professionals in controlled laboratory environments following validated procedures. Discard if the solution shows any cloudiness or particulate matter.
What is the difference between research-grade and pharmaceutical-grade Reconstitution Solution?
They are distinct classifications. Research-grade material is supplied for laboratory research use only and is characterised by the analytical panel published on this page. Pharmaceutical-grade is a separate regulatory classification governing material intended for human use. Astramide supplies research-grade material and makes no pharmaceutical-grade claim.
Does benzyl alcohol affect peptide stability?
Published formulation research has examined this directly. Antimicrobial excipients can promote reversible association of peptides in solution, and benzyl alcohol is subject to sorption by some container materials (Meyer et al., 2007, PMID 17722087; Bahal et al., 2002, PMID 11852696). Researchers designing extended storage protocols should account for both effects.
This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.




