Body Protection Compound 157 + Thymosin Beta-4 Fragment

A two-component lyophilized blend of BPC-157 and a thymosin beta-4 fragment
CAS BPC-157: 137525-51-0 Ac-SDKP: 127103-11-1BPC-157: C₆₂H₉₈N₁₆O₂₂ Ac-SDKP: C₂₀H₃₃N₅O₉BPC-157: approximately 1419.5 g/mol Ac-SDKP: approximately 487.5 g/molBlendLyophilized powder

Price range: $90.00 through $792.00

Ships from lot BB20 · 10 mg vial · 99.32% purity · Freedom Diagnostics See the COA

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Tested by an outside labNever in-house
Every lot publishedIncluding rejected lots
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SKU: N/A Category:
BATCH
VERIFICATION
LOT NUMBER
BB20
10 mg vial
IDENTITY
Confirmed
CHROMATOGRAPHIC PURITY
99.32%
NET CONTENT — AC-SDKP
11.8 mg
Analytical characterization

Every result against its specification.

Lot BB20 · 10 mg vial · Freedom Diagnostics · reported 9 June 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterion Above criterion Not on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
LC-MS
LC-MS match to the labelled compound
Confirmed
WITHIN SPEC
Chromatographic purity
HPLC-UV
at or above 98.0%
99.32%
95 at or above 98.0% 100
WITHIN SPEC
Net content — Ac-SDKP
HPLC-UV
11.8 mg
80 120
REPORTED
Net content — BPC-157
HPLC-UV
11.22 mg
80 120
REPORTED
Endotoxin
LAL, USP <85>
below the 0.05 EU/mL assay sensitivity
Pass, 2 of 2 at ≤0.05 EU/mL
WITHIN SPEC
Appearance
Visual
white lyophilized powder
White Lyophilized Powder
WITHIN SPEC
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Certificate of Analysis
Body Protection Compound 157 + Thymosin Beta-4 Fragment · Lot BB20 · 10 mg vial · Lab No. 2606080482
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Quick reference

How to read this report

Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile

Body Protection Compound 157 + Thymosin Beta-4 Fragment, in structural terms.

Sequence
BPC-157: GEPPPGKPADDAGLV Thymosin Beta-4 Fragment (Ac-SDKP): Ac-Ser-Asp-Lys-Pro
Molecular formula
BPC-157: C₆₂H₉₈N₁₆O₂₂ Ac-SDKP: C₂₀H₃₃N₅O₉
Molecular weight
BPC-157: approximately 1419.5 g/mol Ac-SDKP: approximately 487.5 g/mol
CAS number
BPC-157: 137525-51-0 Ac-SDKP: 127103-11-1
Structure type
Blend
Primary molecular target
BPC-157: Multiple experimentally investigated cellular signaling pathways, including endothelial and angiogenesis-associated signaling. Ac-SDKP: TGF-β/Smad-associated signaling, fibroblast-associated pathways, extracellular-matrix regulation, and endothelial-cell signaling. Because this is a combination research product, there is no single established molecular target shared by both components.
Physical form
Lyophilized powder

This research formulation contains two distinct peptide structures: BPC-157, a synthetic 15-amino-acid peptide, and Ac-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline), an N-terminally acetylated tetrapeptide derived from Thymosin Beta-4. Independent LC-MS analysis of the tested product identified both BPC-157 and Ac-SDKP as the constituent analytes. These are the individual molecular formulas of the two components rather than a single molecular formula for the combined formulation. Molecular weights are reported separately because this is a two-component research formulation.

Research profile

Where Body Protection Compound 157 + Thymosin Beta-4 Fragment appears in the literature.

Cell Biology; Molecular Biology; Vascular Biology; Fibroblast Biology; Extracellular-Matrix Research; Peptide Biology
Research applications
  • Peptide signaling research
  • Cellular migration studies
  • Endothelial-cell research
  • Angiogenesis-associated experimental models
  • Fibroblast biology
  • Extracellular-matrix research
  • Collagen-production models
  • TGF-β-associated signaling studies
Experimental systems
  • Experimental systems reported in research involving the individual components include:
  • Cultured endothelial-cell systems
  • Fibroblast cell-culture models
  • Human cardiac fibroblast models
  • Endothelial proliferation and migration models
  • Extracellular-matrix experimental systems
  • Angiogenesis-associated models
  • Preclinical tissue-response models
Specific assays
  • Cell migration assays
  • Endothelial proliferation assays
  • Tube-formation assays
  • Fibroblast differentiation assays
  • Collagen-expression assays
  • Western blot / protein-expression analysis
  • TGF-β/Smad signaling assays
  • ERK1/2 pathway analysis
Measured endpoints
  • Experimental endpoints reported in research involving the individual components include:
  • Cellular migration
  • Endothelial-cell proliferation
  • Tube formation
  • Fibroblast differentiation
  • Collagen production
  • Extracellular-matrix signaling
  • TGF-β/Smad pathway activity
Pcs

Single Vial, 3-Pack, 6-Pack, Pack of 10

Strength

10mg

Mechanism and research context

What has been studied, and in what systems.

Body Protection Compound 157 + Thymosin Beta-4 Fragment combines two analytically distinct peptides investigated across different areas of experimental biology.

BPC-157 has been investigated in preclinical models involving cellular signaling, endothelial responses, angiogenesis-associated pathways, cellular migration, and tissue-response mechanisms.

The Thymosin Beta-4-derived component identified in the tested formulation is Ac-SDKP. Ac-SDKP has been investigated experimentally in fibroblast biology, extracellular-matrix regulation, TGF-β/Smad signaling, inflammatory pathways, endothelial-cell migration, and angiogenesis-associated models.

The current COA establishes the presence of BPC-157 and Ac-SDKP, but does not establish that the combination produces synergistic or additive biological effects.

These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.

Cited literature

Vukojevic J et al., 2022. Pentadecapeptide BPC 157 and the central nervous system. Neural Regen Res. PMID 34380875. https://pubmed.ncbi.nlm.nih.gov/34380875/

Yildirim AK et al., 2026. Endothelium-Dependent Nitric Oxide-Mediated Vasorelaxant Effects of BPC 157 in Human Internal Mammary Artery. J Clin Med. PMID 42123221. https://pubmed.ncbi.nlm.nih.gov/42123221/

Hannappel E et al., 2007. beta-Thymosins. Ann N Y Acad Sci. PMID 17468232. https://pubmed.ncbi.nlm.nih.gov/17468232/

Evidence level
Preclinical Research This is the appropriate classification because the research context described above is predominantly derived from laboratory and preclinical investigation. It should not be presented as established clinical efficacy.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Research Overview

Read our research write-up on this compound:

Frequently asked questions

About this compound and its batch data.

What purity did this Body Protection Compound 157 + Thymosin Beta-4 Fragment batch achieve?

Lot BB20 was analysed by Freedom Diagnostics and returned chromatographic purity of 99.32% by HPLC with UV detection coupled to mass spectrometry. Identity was confirmed by mass spectral match. The full certificate is published on this page, and every figure shown here is taken from it.

How much Body Protection Compound 157 + Thymosin Beta-4 Fragment is in the vial?

This is a multi-component preparation, so content is reported per component: Ac-SDKP 11.8 mg (118% of label), BPC-157 11.22 mg (112.2% of label). Astramide publishes the measured figures rather than the label claim.

Was this Body Protection Compound 157 + Thymosin Beta-4 Fragment batch tested for endotoxins?

Yes. Endotoxin testing was performed using the Limulus Amebocyte Lysate assay in accordance with USP , and this batch returned Pass, 2 of 2 at ≤0.05 EU/mL. The result appears on the certificate published on this page.

How should Body Protection Compound 157 + Thymosin Beta-4 Fragment be stored for research use?

As supplied, the lyophilized powder should be held at -20°C and protected from light and moisture. Once reconstituted, store at 2-8°C and use within 14 to 30 days. Avoid repeated freeze-thaw cycles and follow the handling procedures appropriate to your laboratory.

What is the difference between research-grade and pharmaceutical-grade Body Protection Compound 157 + Thymosin Beta-4 Fragment?

These are separate classifications. Research-grade material is supplied for laboratory research use only and is not intended for human or animal consumption. Pharmaceutical-grade is an FDA classification that applies to drugs manufactured for human use. Astramide supplies research-grade material only.

How can I verify this Body Protection Compound 157 + Thymosin Beta-4 Fragment certificate independently?

The certificate was issued by Freedom Diagnostics under lot BB20, laboratory reference 2606080482. Quote that reference to the laboratory directly. The same document is published here in full, and is not summarised or reformatted by Astramide.

Research use only

This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.

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