HCG

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Batch Number: 26044

Purity Percentage: 99.70

Identity Confirmation: Confirmed

Testing Methods: HPLC-MS HPLC-UV

Credential Line:

Test Date: 02/03/2026

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SKU: N/A Category:

All research compounds supplied by OPTMZ Peptides are intended strictly for laboratory research applications and are not designed for medical use. These materials are not approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease. By purchasing, the buyer confirms use strictly for scientific research purposes and not for human or animal consumption.

Product Overview

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone investigated in controlled laboratory environments for its interaction with the luteinizing hormone/choriogonadotropin receptor (LHCGR).

HCG is composed of alpha and beta subunits and is structurally related to other glycoprotein hormones. Research involving HCG includes receptor signaling, gonadal steroidogenesis, reproductive endocrinology, Leydig-cell biology, ovarian signaling, and hypothalamic-pituitary-gonadal axis research.

Unlike the synthetic peptides in much of the OPTMZ Peptides catalog, HCG is a glycoprotein hormone rather than a conventional short synthetic peptide.

Research Data

Research Classification

Gonadotropin / Glycoprotein Hormone / LHCGR Agonist

Structure Description

Human Chorionic Gonadotropin is a heterodimeric glycoprotein hormone composed of noncovalently associated alpha (α) and beta (β) subunits. The alpha subunit is shared structurally with other glycoprotein hormones, while the beta subunit contributes to HCG-specific molecular recognition. HCG contains multiple glycosylation sites that contribute substantially to its molecular mass, structural properties, and biological behavior.

Research Discipline

Reproductive Endocrinology; Molecular Endocrinology; Glycoprotein Hormone Biology; Receptor Pharmacology; Gonadal Biology; Reproductive Biology

Molecular Formula

Complex glycoprotein — no single practical fixed molecular formula This is the scientifically cleaner entry for HCG. Because HCG is a glycosylated protein hormone with heterogeneous carbohydrate structures, representing it with a simple molecular formula in the same manner as a small synthetic peptide can be misleading.

Molecular Weight

Approximately 36.7 kDa (intact glycoprotein; glycosylation-dependent)

CAS Number

9002-61-3

Amino Acid Sequence

Heterodimeric glycoprotein composed of α- and β-subunits.

Alpha subunit: approximately 92 amino acids.

HCG-specific beta subunit: approximately 145 amino acids.

For this ACF field, I recommend not inserting one long sequence string as though HCG were a conventional linear peptide. The α/β heterodimeric structure and glycosylation are scientifically important characteristics of the molecule.

Primary Molecular Target

Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR; LH/CG Receptor)

Experimental Applications

LHCGR receptor signaling studies
Gonadotropin receptor research
Leydig-cell signaling
Steroidogenesis research
Ovarian-cell signaling
Corpus luteum research
cAMP signaling studies
Reproductive endocrine research
Gonadal cell biology
Glycoprotein hormone structure-function studies
Comparative LH/HCG receptor research
HPG-axis research

Experimental Systems

Relevant experimental systems include:

LHCGR-expressing cell systems
Leydig-cell models
Ovarian-cell models
Granulosa-cell systems
Theca-cell systems
Gonadal tissue models
Receptor-transfected cell systems
Steroidogenesis models
cAMP signaling systems
Glycoprotein hormone receptor models
Reproductive endocrine research systems

Specific Assays

HCG potency / IU assays
Chromatographic purity analysis
Immunoassays
ELISA
LHCGR receptor-binding assays
Receptor activation assays
cAMP accumulation assays
Steroidogenesis assays
Testosterone production assays
Progesterone production assays
Cell-response assays
Western blot analysis
Protein quantification assays

Measured Endpoints

HCG biological activity / IU
Analytical purity
LHCGR activation
Intracellular cAMP response
Steroidogenic response
Testosterone production
Progesterone production
Gonadotropin-receptor activity
Cellular signaling response
Receptor-binding activity

Lot-specific measured endpoints on the supplied report: HCG content expressed in IU and purity.

Mechanism / Research Context

Human Chorionic Gonadotropin interacts with the luteinizing hormone/choriogonadotropin receptor (LHCGR), a G-protein-coupled receptor expressed in gonadal tissues.

LHCGR activation is associated with intracellular G-protein signaling and increased cyclic AMP (cAMP), initiating downstream pathways involved in steroidogenic enzyme regulation and gonadal hormone synthesis.

In experimental Leydig-cell systems, HCG/LHCGR signaling is commonly used to investigate pathways associated with testosterone biosynthesis. In ovarian research systems, the same receptor pathway is studied in relation to follicular, luteal, and steroidogenic signaling.

Because HCG and luteinizing hormone interact with the same receptor, HCG is also useful in comparative investigations of LH/HCG receptor pharmacology and gonadotropin signaling.

Evidence Level

Established Clinical Research HCG has an extensive experimental, biochemical, and clinical literature. This evidence classification describes the scientific evidence surrounding the HCG molecule, not the regulatory status or intended use of the OPTMZ research material.

Research References

For this field, I would use authoritative HCG/LHCGR literature covering: Human Chorionic Gonadotropin (HCG) — molecular structure, α/β subunits, glycosylation, and endocrine biology. Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) — receptor pharmacology and intracellular signaling. Gonadotropin signaling literature — HCG-induced cAMP signaling and steroidogenesis. Reproductive endocrinology literature — Leydig-cell, ovarian, corpus luteum, and gonadal signaling research. For the lot-specific analytical reference, use: Waiida Testing Technology Co., Ltd. — HCG Test Report, Task #26044, Batch 2026/02, analysis conducted March 2, 2026.

Analytical Characterization

ndependent analytical testing of HCG, Batch 2026/02, by Waiida Testing Technology reported:

1,000 IU specification: 1,066.56 IU measured; 99.70% purity
2,000 IU specification: 2,127.01 IU measured; 99.78% purity
5,000 IU specification: 5,372.33 IU measured; 99.70% purity
10,000 IU specification: 10,605.14 IU measured; 99.64% purity
Physical Form: Powder
Task Number: #26044
Batch: 2026/02
Analysis Conducted: March 2, 2026
Verification Key: WYD260104GN044

Endotoxin testing: Not reported on the supplied test report.

This last point is important for your site database: do not mark this HCG batch as endotoxin PASS. It belongs in the “Not Tested / Not Reported” category based on the document you supplied.

Research Keywords

HCG, Human Chorionic Gonadotropin, Human Chorionic Gonadotrophin, Gonadotropin, Glycoprotein Hormone, HCG Research, LHCGR, LH/CG Receptor, Luteinizing Hormone Receptor, Gonadotropin Receptor, Reproductive Endocrinology, Leydig Cell Research, Ovarian Research, Steroidogenesis, Testosterone Biosynthesis, Progesterone Signaling, Corpus Luteum, cAMP Signaling, HPG Axis, Glycoprotein Hormone Research, HCG 1000 IU, HCG 2000 IU, HCG 5000 IU, HCG 10000 IU

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Product Description

Technical Specifications

  • Product: HCG
  • Full Name: Human Chorionic Gonadotropin
  • Research Classification: Gonadotropin / Glycoprotein Hormone
  • Compound Type: Heterodimeric Glycoprotein Hormone
  • Primary Molecular Target: Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR)
  • Physical Form: Powder
  • Batch: 2026/02
  • Manufacturer: Shandong Rou Er dan Kang International Trade Co., Ltd.
  • Testing Laboratory: Waiida Testing Technology Co., Ltd.
  • Task Number: #26044
  • Analysis Date: March 2, 2026
  • Test Verification Key: WYD260104GN044

Available/Tested Specifications

Label Specification Measured Content Purity
1,000 IU 1,066.56 IU 99.70%
2,000 IU 2,127.01 IU 99.78%
5,000 IU 5,372.33 IU 99.70%
10,000 IU 10,605.14 IU 99.64%

These are the values shown directly on the supplied Waiida Test Report.

Analytical & Testing

The submitted HCG product was evaluated by Waiida Testing Technology under Task Number #26044.

The report provides:

  • 1,000 IU: 1,066.56 IU measured; 99.70% purity
  • 2,000 IU: 2,127.01 IU measured; 99.78% purity
  • 5,000 IU: 5,372.33 IU measured; 99.70% purity
  • 10,000 IU: 10,605.14 IU measured; 99.64% purity
  • Physical Form: Powder
  • Batch: 2026/02
  • Analysis Conducted: March 2, 2026

All four tested specifications therefore report >99.6% purity.

Important: This report does not show an endotoxin test or endotoxin result. For the website, I would classify endotoxin status for this HCG as Not Tested / Not Reported on Current COA, rather than Pass or Fail.

Handling & Storage

HCG should be handled by qualified professionals in controlled laboratory environments. Appropriate storage conditions should be maintained to preserve glycoprotein integrity and analytical consistency.

Avoid unnecessary exposure to heat, moisture, light, and repeated temperature fluctuations. Experimental preparation, storage, and handling should follow validated laboratory procedures appropriate to the intended research application.

Research Context

Human Chorionic Gonadotropin is investigated extensively in reproductive and endocrine research.

Research areas include:

  • LHCGR receptor signaling
  • Gonadotropin receptor biology
  • Leydig-cell signaling
  • Ovarian-cell signaling
  • Steroidogenesis
  • Testosterone biosynthesis pathways
  • Progesterone-associated signaling
  • Corpus luteum biology
  • Reproductive endocrinology
  • Gonadal cell signaling
  • cAMP-mediated receptor signaling
  • Glycoprotein hormone structure-function research
  • HPG-axis research

HCG interacts with the same receptor system as luteinizing hormone—the luteinizing hormone/choriogonadotropin receptor (LHCGR). This receptor interaction makes HCG an established experimental tool for investigating gonadal signaling and steroidogenic pathways.

These research contexts describe the scientific literature surrounding HCG and do not establish intended use of this particular research product in humans or animals.

Research Application Scope

HCG is relevant to experimental investigations involving reproductive endocrinology, LHCGR activation, gonadal steroidogenesis, Leydig-cell function, ovarian signaling, receptor-mediated cAMP signaling, and glycoprotein hormone biology.

Its established receptor pharmacology also makes HCG useful in comparative research involving luteinizing hormone, gonadotropin receptors, receptor activation, and downstream intracellular signaling.

Use Statement

For laboratory research use only. Intended strictly for in vitro and controlled experimental research applications.

Disclaimer

All products currently listed on this site are for research purposes ONLY.

Pcs

Single Vial, Pack Of 10

Strength

10,000iu

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