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SLU-PP-332 Liquid Pro research solution, 1 mg/mL, 30 mL vial and box

SLU-PP-332 Liquid – Pro

Pro Series
SLU-PP-332, a synthetic estrogen-related receptor (ERR) agonist, as a 1 mg/mL solution
CAS 303760-60-3C₁₈H₁₄N₂O₂290.32 g/molReagentSolution

$89.99

Ships from lot 202609SLU_L · 1 mg/mL solution · 99.21% purity · Hyte Research Division See the COA

UPS Ground $9.95. Free at $150. Orders before 2 pm ET ship the same business day.

Why the Pro Series costs more
  • Synthesized in the USA. Domestic ground and air only, no ocean freight.
  • Released only above 99% HPLC purity.
  • Its own lot and its own published certificate.
How the Pro Series is made and tested
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Tested by an outside labNever in-house
Every lot publishedIncluding rejected lots
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BATCH
VERIFICATION
LOT NUMBER
202609SLU_L
1 mg/mL solution
IDENTITY
Conforms to reference standard
CHROMATOGRAPHIC PURITY
99.21%
CONCENTRATION
1.12 mg/mL (112% of 1 mg/mL label claim)
Analytical characterization

Every result against its specification.

Lot 202609SLU_L · 1 mg/mL solution · Hyte Research Division · reported 12 October 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterion Above criterion Not on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
HPLC-DAD, against reference standard
Conforms to reference standard
Conforms to reference standard
WITHIN SPEC
Chromatographic purity
HPLC-DAD
at or above 99.0%
99.21%
95 at or above 99.0% 100
WITHIN SPEC
Concentration
HPLC-DAD
at or above 90% of label claim (0.9 mg/mL)
1.12 mg/mL (112% of 1 mg/mL label claim)
80 at or above 90% of label claim (0.9 mg/mL) 120
WITHIN SPEC
Appearance
Visual
clear liquid
Clear liquid
WITHIN SPEC
Endotoxin
LAL
—
Not reported on this certificate
NOT REPORTED
Microbial panel
—
Not reported on this certificate
NOT REPORTED
Heavy metals
—
Not reported on this certificate
NOT REPORTED
Residual solvents
—
Not reported on this certificate
NOT REPORTED
Sterility
—
Not reported on this certificate
NOT REPORTED
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Certificate of Analysis
SLU-PP-332 Liquid - Pro · Lot 202609SLU_L · 1 mg/mL solution · Lab No. AST#00005
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Quick reference

How to read this report

Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile

SLU-PP-332 Liquid - Pro, in structural terms.

Sequence
Not applicable. SLU-PP-332 is a small molecule, not a peptide. Chemical name: 4-hydroxybenzoic acid 2-(2-naphthalenylmethylene)hydrazide
Molecular formula
C₁₈H₁₄N₂O₂
Molecular weight
290.32 g/mol
CAS number
303760-60-3
Structure type
Reagent
Parent sequence
Not applicable (small molecule)
Primary molecular target
Estrogen-related receptors ERRα, ERRβ and ERRγ, a family of orphan nuclear receptors. Billon et al. (2023) described SLU-PP-332 as a pan-ERR agonist with the highest potency at ERRα.
Physical form
Solution

SLU-PP-332 is a synthetic small molecule, an N-acylhydrazone formed from 4-hydroxybenzoic acid hydrazide and 2-naphthaldehyde. It is not a peptide. Its molecular formula is C18H14N2O2 and its molecular weight is 290.32 g/mol. This product is supplied as a clear solution at a nominal 1 mg/mL in a sealed 30 mL bottle.

Research profile

Where SLU-PP-332 Liquid - Pro appears in the literature.

Nuclear Receptor Pharmacology; Mitochondrial Biology; Medicinal Chemistry; Analytical Chemistry
Research applications
  • Published experimental use of SLU-PP-332 includes:
  • ERRα, ERRβ and ERRγ agonist activity in cell-based reporter assays
  • Mitochondrial function and cellular respiration in a skeletal muscle cell line
  • ERR-dependent gene expression profiling
  • Structure-activity relationship studies of the SLU-PP-332 scaffold
  • In vitro metabolism and analytical characterization by LC-HRMS/MS
  • These areas describe experimental research contexts and do not establish efficacy or safety in humans.
Experimental systems
  • Experimental systems reported in the SLU-PP-332 literature include:
  • Cell-based nuclear receptor reporter systems
  • Skeletal muscle cell lines
  • Mouse models
  • Human liver S9 fraction and liver microsome preparations
  • Computational docking and molecular dynamics models
Specific assays
  • Assay formats reported in the SLU-PP-332 literature include:
  • Cell-based ERR transcriptional reporter assays
  • Cellular respiration measurement
  • Gene expression analysis
  • Liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS/MS)
  • Nuclear magnetic resonance (NMR) spectroscopy of metabolites
Measured endpoints
  • Endpoints reported in published SLU-PP-332 research include:
  • ERRα, ERRβ and ERRγ agonist potency
  • Mitochondrial function and respiration in cultured cells
  • ERR target gene expression
  • Phase I and Phase II metabolite identity
  • Research use only. Not for human or animal consumption.
Size

30 mL
Mechanism and research context

What has been studied, and in what systems.

SLU-PP-332 was first reported by Billon et al. (2023) as a synthetic agonist of all three estrogen-related receptors, ERRα, ERRβ and ERRγ, with the highest potency at ERRα. ERRs are orphan nuclear receptors studied for their role in mitochondrial gene regulation. In that work, SLU-PP-332 increased mitochondrial function and cellular respiration in a skeletal muscle cell line, and the authors also studied it in mice.

Okda et al. (2026) mapped the structure-activity relationship of the SLU-PP-332 scaffold, combining synthesis, cell-based assays, gene expression profiling and computational modeling to identify which parts of the molecule control ERRα and ERRγ activity.

Möller et al. (2026) characterized SLU-PP-332 by LC-HRMS/MS and identified nine in vitro metabolites formed by human liver S9 fraction and microsomes.

These studies describe cell, animal and chemical systems. They do not describe effects in people.

These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.

Cited literature

Billon C et al., 2023. Synthetic ERRα/β/γ agonist induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chem Biol. PMID 36988910. https://pubmed.ncbi.nlm.nih.gov/36988910/
Okda HE et al., 2026. Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling. Int J Biol Macromol. PMID 41850449. https://pubmed.ncbi.nlm.nih.gov/41850449/
Möller T et al., 2026. In vitro metabolism and analytical characterization of SLU-PP-332 and SLU-PP-915: novel pan-ERR agonists with doping potential. Rapid Commun Mass Spectrom. PMID 41588687. https://pubmed.ncbi.nlm.nih.gov/41588687/

Evidence level
Preclinical and investigational. SLU-PP-332 is not approved by the FDA for any use. Statements on this page describe published in vitro, animal and analytical studies only. They do not establish efficacy or safety in humans.
Handling and storage
As supplied
Solution in a sealed container, as stated on the product label.
Storage
Store per the conditions printed on the label. Keep tightly closed and protected from light and heat.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions

About this compound and its batch data.

What is SLU-PP-332?

SLU-PP-332 is a synthetic small molecule studied as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ. It is not a peptide. Its molecular formula is C18H14N2O2, its molecular weight is 290.32 g/mol and its CAS number is 303760-60-3. Astramide supplies it as a clear 1 mg/mL solution in a sealed 30 mL bottle. Sold for research use only.

What has SLU-PP-332 been examined for in published research?

Published research on SLU-PP-332 is preclinical. Billon et al. (2023, ACS Chem Biol, PMID 36988910) reported it as a pan-ERR agonist with the highest potency at ERRα and measured mitochondrial function in a skeletal muscle cell line. Later work has mapped its structure-activity relationships and in vitro metabolism. Astramide makes no claim about outcomes in humans.

What purity does the current SLU-PP-332 Liquid Pro lot reach?

The current lot is 202609SLU_L. HPLC-DAD analysis by Hyte Research Division measured chromatographic purity of 99.21%, and identity conformed to a reference standard. The results are on report AST#00005, reported October 12, 2026. The full certificate is published with the lot record, which can be looked up by the lot number printed on the bottle.

What concentration is in the bottle?

The label claim is 1 mg/mL in a 30 mL bottle. For lot 202609SLU_L, Hyte Research Division measured 1.12 mg/mL, which is 112% of the label claim. The laboratory specification is not less than 90% of label claim (0.9 mg/mL). The figure is published exactly as the laboratory reported it.

How was this lot tested?

This lot was tested by Hyte Research Division, an independent laboratory. The certificate covers purity, identity and quantity by HPLC-DAD, with identity checked against a reference standard. Mass spectrometry, endotoxin, microbial testing, heavy metals, residual solvents and sterility were not part of this certificate. Every reported result is published with the lot record.

How should SLU-PP-332 Liquid Pro be stored?

Keep the bottle sealed, upright and protected from light, at the storage temperature printed on the bottle label. Avoid heat and repeated temperature cycling. Once the seal is pierced, handle the solution with clean laboratory technique to avoid contamination. Handle only in a controlled laboratory setting by qualified professionals.

What are estrogen-related receptors?

Estrogen-related receptors (ERRα, ERRβ and ERRγ) are orphan nuclear receptors: no natural ligand has been confirmed for them. Despite the name, they do not bind estrogen. They are studied mainly for their role in regulating genes involved in mitochondrial function and energy metabolism in cells.

What does Pro Series mean?

SLU-PP-332 Liquid Pro is part of the Astramide Pro Series. It is made in the USA, released under its own lot, and released only when HPLC purity measures at or above 99%. The current lot measured 99.21%. The certificate for each lot is published with its lot record.

Research use only

This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.

COA library Every lot we have tested Search by batch number. Past lots stay published. How we test The analytical panel What each method measures and the criterion each lot must meet. Open Lab Send us your peptides Any vendor. Same lab. Your own Certificate of Analysis.
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