Research Use Only

All research peptides supplied by OPTMZ Peptides are intended strictly for laboratory research applications and are not designed for medical use. These materials are not approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease. By purchasing, the buyer confirms use strictly for scientific research purposes and not for human or animal consumption.

Product Overview

ACE-031 is a recombinant research protein engineered from the extracellular ligand-binding domain of activin receptor type IIB (ActRIIB) fused to an immunoglobulin Fc domain. It has been investigated experimentally for its interaction with members of the transforming growth factor-beta (TGF-β) superfamily, including myostatin and related ligands involved in cellular growth and differentiation signaling.

ACE-031 functions experimentally as a soluble ligand-binding protein, making it useful in controlled laboratory studies examining ActRIIB-associated signaling, myostatin biology, skeletal-muscle signaling pathways, and TGF-β superfamily interactions

Technical Specifications

Product: ACE-031
Quantity: 1 mg
Research Classification: ActRIIB-Fc fusion protein
Target Pathway: Activin receptor type IIB (ActRIIB) ligand signaling
Purity: 99.09% (HPLC-UV tested, current lot)
Identity: Confirmed by LC-MS
Form: White lyophilized powder
Measured Net Content: 1.28 mg
Lot: ACE1

Analytical & Testing

Each tested batch of ACE-031 undergoes analytical evaluation to verify identity, purity, and analytical consistency. A corresponding Certificate of Analysis (COA) is available for the tested lot.

For the current OPTMZ Peptides lot, independent testing reported:

Identity (LC-MS): ACE-031 — Confirmed
Purity (HPLC-UV): 99.09%
Measured Net Content: 1.28 mg
Appearance: White lyophilized powder
Endotoxin Replicate 1: Pass
Endotoxin Replicate 2: Pass
Assay Sensitivity: ≤0.05 EU/mL
Lot: ACE1

The laboratory reports HPLC with UV detection coupled with mass spectrometry (LC-MS), while endotoxin testing was performed using a Limulus Amebocyte Lysate assay in accordance with USP <85> under validated laboratory conditions.

Handling & Storage

ACE-031 should be handled by qualified professionals in controlled laboratory environments. Appropriate storage conditions should be maintained to preserve protein stability and structural integrity.

Avoid unnecessary exposure to heat, moisture, and repeated temperature fluctuations. Experimental preparation and handling procedures should follow validated laboratory protocols appropriate to the research application.

Research Context

ACE-031 has been investigated in controlled experimental systems involving TGF-β superfamily signaling and ActRIIB-associated pathways. Research areas include:

Activin receptor type IIB pathway research
Myostatin-associated signaling
TGF-β superfamily ligand interactions
Skeletal-muscle biology
Cellular growth and differentiation pathways
Ligand-receptor binding models
Protein signaling mechanisms
ActRIIB pathway modulation

These observations relate to experimental research and do not establish therapeutic efficacy or safety for human use.

Research Application Scope

ACE-031 continues to be relevant to experimental biology involving ActRIIB ligand interactions and TGF-β superfamily signaling.

Its engineered soluble receptor structure allows researchers to investigate ligand sequestration and downstream signaling associated with myostatin, activins, and related signaling proteins in controlled experimental models.

Use Statement

For laboratory research use only. Intended strictly for in vitro research applications.

Disclaimer

All products currently listed on this site are for research purposes ONLY.

Pcs	Single Vial, Pack Of 10

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