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DSIP Pro research peptide vial and box
DSIP - Pro
  1. DSIP Pro research peptide vial and box
  2. DSIP - Pro

DSIP – Pro

Pro Series
DSIP (delta sleep-inducing peptide), a nine-amino-acid neuropeptide
CAS 62568-57-4C₃₅H₄₈N₁₀O₁₅Approximately 848.8 g/mol9 amino acidsLinear peptideLyophilized powder

Price range: $35.00 through $320.00

Ships from lot NHS-DIS05-20260913-01 · 5 mg vial · 99% purity · pH Solutions Lab See the COA
Why the Pro Series costs more
  • Synthesized in the USA. Domestic ground and air only, no ocean freight.
  • Released only above 99% HPLC purity.
  • Its own lot and its own published certificate.
How the Pro Series is made and tested
Ships from Austin, TexasUnited States only
Tested by an outside labNever in-house
Every lot publishedIncluding rejected lots
Same-day dispatchOn orders before 2pm ET
SKU: N/A Category: Tags: ,
BATCH
VERIFICATION
LOT NUMBER
NHS-DIS05-20260913-01
5 mg vial
IDENTITY
Match (C35H48N10O15, 848.8 g/mol)
CHROMATOGRAPHIC PURITY
99%
NET CONTENT
4.9574 mg (99.148% of 5 mg label claim)
Analytical characterization

Every result against its specification.

Lot NHS-DIS05-20260913-01 · 5 mg vial · pH Solutions Lab · reported 29 September 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterion Above criterion Not on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
Match to the labelled compound
Match (C35H48N10O15, 848.8 g/mol)
WITHIN SPEC
Chromatographic purity
HPLC (220 nm)
at or above 99.0%
99%
95 at or above 99.0% 100
WITHIN SPEC
Net content
4.9574 mg (99.148% of 5 mg label claim)
80 120
REPORTED
Appearance
Visual
white lyophilized powder
White to off-white lyophilized powder
WITHIN SPEC
Water content
Karl Fischer
reported
0.0%
WITHIN SPEC
pH
reported
7.0
WITHIN SPEC
Water activity
within laboratory limit
0.423 aw, pass
WITHIN SPEC
Microbial panel
not detected
Pass, 10 organisms and counts not detected
WITHIN SPEC
Heavy metals
within laboratory limits
Pass. As, Cd, Pb, Hg each 0.000 ppm
WITHIN SPEC
Residual solvents
within laboratory limits
Pass, 12 solvents each 0.000 ppm
WITHIN SPEC
Sterility
sterile
Pass
WITHIN SPEC
Mycotoxins
within laboratory limits
Pass
WITHIN SPEC
Endotoxin
LAL
—
Not reported on this certificate
NOT REPORTED
Values are reported per vial unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Certificate of Analysis
DSIP - Pro · Lot NHS-DIS05-20260913-01 · 5 mg vial · Lab No. NHS-DIS05-20260913-01
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Quick reference

How to read this report

Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your vial. If they differ, this report is not for your vial.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much peptide is in the vial, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile

DSIP - Pro, in structural terms.

DSIP - Pro molecular structure
Sequence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)
Molecular formula
C₃₅H₄₈N₁₀O₁₅
Molecular weight
Approximately 848.8 g/mol
CAS number
62568-57-4
Peptide length
9 amino acids
Structure type
Linear peptide
Parent sequence
Originally isolated from rabbit cerebral venous blood; no precursor protein has been established
Primary molecular target
No specific receptor has been identified for DSIP. Reviews describe its mechanism as unresolved; published studies have examined its effects on pineal N-acetyltransferase activity involving the alpha-1 adrenergic receptor.
Physical form
Lyophilized powder
PubChem CID
68816

DSIP is a linear nine-amino-acid peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE), with a free N-terminus and a free C-terminal carboxylic acid. It was isolated in the 1970s from the cerebral venous blood of rabbits, and its sequence was determined and confirmed by synthesis. It is glycine-rich, and its only aromatic residue is the N-terminal tryptophan.

Research profile

Where DSIP - Pro appears in the literature.

Neurobiology; Neuroendocrinology; Peptide Chemistry; Pineal Biology
Research applications
  • Published studies have used DSIP in:
  • Peptide isolation, sequencing and synthesis studies
  • Pineal N-acetyltransferase activity studies
  • Neuropeptide structure-activity studies
  • Studies of DSIP-like immunoreactive material in tissues
Experimental systems
  • Rat pineal gland preparations
  • Ovine pineal tissue extracts
  • Rabbit and rat models used in neurophysiology studies
  • Synthetic peptides for analytical and structural work
Specific assays
  • Amino acid analysis and sequencing
  • Peptide synthesis and chromatographic comparison
  • N-acetyltransferase enzyme activity assays
  • Electroencephalographic (EEG) recording in animal models
  • Radioimmunoassay for DSIP-like material
Measured endpoints
  • Primary amino acid sequence
  • Pineal N-acetyltransferase activity
  • EEG patterns in animal models
  • Tissue levels of DSIP-like material
Pcs

Single Vial, Pack of 10
Strength

5mg
Mechanism and research context

What has been studied, and in what systems.

DSIP was isolated from the cerebral venous blood of rabbits in the 1970s, and its nine-amino-acid sequence was determined and confirmed by chemical synthesis (Schoenenberger et al., 1978).

Later studies in rat pineal gland preparations examined how DSIP modulates stimulation of the enzyme N-acetyltransferase, and found that the effect involved the alpha-1 adrenergic receptor (Graf and Schoenenberger, 1987).

Despite decades of work, no specific receptor or precursor gene for DSIP has been identified, and a review has described it as a still unresolved riddle (Kovalzon and Strekalova, 2006). These studies place DSIP in neuropeptide and neuroendocrine research.

These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.

Cited literature

Schoenenberger GA et al., 1978. The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide. Pflugers Arch. PMID 568769. https://pubmed.ncbi.nlm.nih.gov/568769/
Graf MV, Schoenenberger GA, 1987. Delta sleep-inducing peptide modulates the stimulation of rat pineal N-acetyltransferase activity by involving the alpha 1-adrenergic receptor. J Neurochem. PMID 3029331. https://pubmed.ncbi.nlm.nih.gov/3029331/
Kovalzon VM, Strekalova TV, 2006. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. PMID 16539679. https://pubmed.ncbi.nlm.nih.gov/16539679/

Evidence level
The structure of DSIP is well established, but its receptor and mechanism remain unresolved. Published work is biochemical, tissue-based and animal-model research. Statements on this page describe experimental systems, not outcomes in humans.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions

About this compound and its batch data.

What is DSIP peptide?

DSIP (delta sleep-inducing peptide) is a linear nine-amino-acid neuropeptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE). Its formula is C35H48N10O15, its molecular weight is about 848.8 g/mol and its CAS number is 62568-57-4. DSIP Pro is supplied as a lyophilized powder in a 5 mg vial. Sold for research use only.

What has DSIP been examined for in published research?

DSIP was isolated from rabbit cerebral venous blood, and its sequence was confirmed by synthesis (Schoenenberger et al., 1978, PMID 568769). Later work examined its effects on pineal N-acetyltransferase activity in rat tissue (Graf and Schoenenberger, 1987, PMID 3029331). A review describes its mechanism as still unresolved (Kovalzon and Strekalova, 2006, PMID 16539679). Astramide makes no claim about outcomes in humans.

Does DSIP have a known receptor?

No. Despite decades of research, no specific receptor or precursor gene has been identified for DSIP, and a 2006 review described it as a still unresolved riddle (Kovalzon and Strekalova, 2006, PMID 16539679). Some studies have linked its effects in pineal tissue to the alpha-1 adrenergic receptor, but that is not a dedicated DSIP receptor.

What purity does the current DSIP Pro lot reach?

Lot NHS-DIS05-20260913-01 returned 99% chromatographic purity by HPLC at 220 nm, reported by pH Solutions Lab on 29 September 2026 under certificate 260918-899-NHS-2. Identity was confirmed as a match to DSIP (C35H48N10O15, 848.8 g/mol). The lot meets the Pro Series release criterion of at or above 99% HPLC purity. The full certificate is published on this page.

How much DSIP is in the vial?

The label claim is 5 mg per vial. For lot NHS-DIS05-20260913-01, the laboratory measured 4.9574 mg of DSIP, which is 99.148% of the label claim. Astramide publishes the measured figure exactly as the laboratory reports it, above or below the label. Net content and chromatographic purity are separate measurements.

How should DSIP be stored for research use?

Lyophilized DSIP is stored at -20°C and protected from light. Once reconstituted, the solution is held at 2 to 8°C and used within 14 to 30 days. Repeated temperature cycling and exposure to moisture should be avoided, because both can affect peptide stability and the comparability of experimental results.

How is Astramide's DSIP Pro tested?

Lot NHS-DIS05-20260913-01 was tested by pH Solutions Lab, an independent ISO/IEC 17025:2017 accredited laboratory (A2LA R243, PJLA Testing #84351). The certificate reports identity, chromatographic purity at 220 nm, net content, water content, pH, water activity, a 10-organism microbial panel, heavy metals, residual solvents, sterility and mycotoxins. Results apply only to this lot.

What does Pro Series mean for DSIP Pro?

DSIP Pro is part of the Astramide Pro Series. It is American-made, synthesized in the USA, and moves by domestic ground and air only, with no ocean freight. It is released under its own lot, and only when HPLC purity measures at or above 99%. The full certificate for each lot is published on this page.

Research use only

This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.

COA library Every lot we have tested Search by batch number. Past lots stay published. How we test The analytical panel What each method measures and the criterion each lot must meet. Open Lab Send us your peptides Any vendor. Same lab. Your own Certificate of Analysis.
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Replacement or store creditOn approved claims. See refund policy.

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