CJC-1295 (without DAC)

CJC-1295 without DAC, a synthetic 29-residue analogue of GHRH
CAS 863288-34-0C₁₅₂H₂₅₂N₄₄O₄₂Approximately 3367.9 g/molLinear peptideLyophilized powder

Price range: $41.00 through $360.00

Ships from lot White Cap · 2 mg vial · 99.31 % purity · Krause Analytical See the COA

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Ships from Austin, TexasUnited States only
Tested by an outside labNever in-house
Every lot publishedIncluding rejected lots
Same-day dispatchOn orders before 2pm ET
BATCH
VERIFICATION
LOT NUMBER
White Cap
2 mg vial
IDENTITY
Confirmed
CHROMATOGRAPHIC PURITY
99.31 %
NET CONTENT
2.04 mg
Analytical characterization

Every result against its specification.

Lot White Cap · 2 mg vial · Krause Analytical · reported 9 February 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterion Above criterion Not on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
HPLC-UV-MS
Mass spectral match to the labelled compound
Confirmed
WITHIN SPEC
Chromatographic purity
HPLC-UV/MS
at or above 98.0%
99.31 %
95 at or above 98.0% 100
WITHIN SPEC
Net content
HPLC-UV-MS
2.04 mg
80 120
REPORTED
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Certificate of Analysis
CJC-1295 (without DAC) · Lot White Cap · 2 mg vial · Lab No. 200510
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Quick reference

How to read this report

Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile

CJC-1295 (without DAC), in structural terms.

CJC-1295 (without DAC) molecular structure
Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ One-letter shorthand: Y-D-A-A-I-F-T-Q-S-Y-R-K-V-L-A-Q-L-S-A-R-K-L-L-Q-D-I-L-S-R-NH₂ A commercial peptide reference lists this sequence for CJC-1295 without DAC.
Molecular formula
C₁₅₂H₂₅₂N₄₄O₄₂
Molecular weight
Approximately 3367.9 g/mol
CAS number
863288-34-0 — COA-reported This is the CAS number reported by Krause Analytical for the actual tested CJC-1295 No DAC sample.
Structure type
Linear peptide
Primary molecular target
Growth Hormone-Releasing Hormone Receptor (GHRHR) Unlike CJC-1295 with DAC, there is no albumin-binding DAC target interaction associated with this form.
Physical form
Lyophilized powder
PubChem CID
91976842

CJC-1295 without DAC is a 29-amino-acid modified GHRH-derived peptide lacking the Drug Affinity Complex present in long-acting CJC-1295. Its structure incorporates substitutions intended to improve stability relative to native GHRH while preserving activity at the growth hormone-releasing hormone receptor.PubChem reports this molecular formula for CJC-1295 without DAC. The molecular weight is consistent with commercial structural records for CJC-1295 without DAC / Modified GRF (1-29).

Research profile

Where CJC-1295 (without DAC) appears in the literature.

Endocrinology; Peptide Biology; GHRH/GH Axis Research; Pituitary Biology; Molecular Signaling; Peptide Pharmacology
Research applications
  • GHRH receptor signaling studies
  • Growth hormone secretion pathway research
  • Pituitary-cell biology
  • Somatotroph signaling studies
  • GH/IGF-1 axis research
  • Peptide stability research
  • GHRH analog structure-function studies
  • Comparative DAC versus non-DAC research
Experimental systems
  • Relevant experimental systems include:
  • GHRH receptor-expressing cell systems
  • Pituitary cell models
  • Somatotroph-associated experimental systems
  • GH secretion assays
  • Endocrine signaling models
  • Modified GHRH biochemical systems
  • Peptide receptor-binding models
Specific assays
  • HPLC-UV chromatographic purity analysis
  • LC-MS identity confirmation
  • Mass-spectrum/reference-spectrum matching
  • GHRH receptor activation assays
  • GH secretion assays
  • Receptor-binding assays
  • cAMP signaling assays
  • Pituitary-cell response assays
Measured endpoints
  • Chromatographic purity
  • Peptide identity
  • Peptide content
  • GHRHR activation
  • Intracellular cAMP signaling
  • Growth hormone release
  • Pituitary-cell response
  • Peptide stability
Pcs

Single Vial, 3-Pack, 6-Pack, Pack of 10

Strength

5mg

Mechanism and research context

What has been studied, and in what systems.

CJC-1295 (without DAC) is investigated primarily as a GHRH analog for experimental study of the growth hormone-releasing hormone receptor and downstream endocrine signaling.
Research areas include:

GHRH receptor signaling
Growth hormone secretion pathways
IGF-1-associated signaling
Pituitary biology
Somatotroph signaling
Endocrine pathway research
GHRH analog structure-function studies
Peptide pharmacology
Modified GRF research
Growth hormone pulse signaling

The non-DAC form is structurally related to Modified GRF (1-29), a stabilized GHRH-derived peptide designed to retain GHRH receptor activity while avoiding the albumin-binding DAC modification.
This distinction is important because much of the published human literature on CJC-1295 specifically concerns the DAC-containing long-acting form, not necessarily the non-DAC peptide. Published CJC-1295 studies therefore should not automatically be used to make pharmacokinetic claims about CJC-1295 without DAC.

These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.

Cited literature

Teichman SL et al., 2006. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. PMID 16352683. https://pubmed.ncbi.nlm.nih.gov/16352683/

Sackmann-Sala L et al., 2009. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. PMID 19386527. https://pubmed.ncbi.nlm.nih.gov/19386527/

Memdouh S et al., 2021. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Test Anal. PMID 34665524. https://pubmed.ncbi.nlm.nih.gov/34665524/

Evidence level
Published experimental and human research. CJC-1295 without DAC appears in the published endocrinology literature, predominantly in biochemical, cellular and animal-model studies, with a smaller body of human investigation. This describes the evidence base around the molecule and does not imply approval or established efficacy.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions

About this compound and its batch data.

What purity did this CJC-1295 without DAC batch achieve?

This lot was analysed by Krause Analytical and returned chromatographic purity of 99.31% by HPLC with UV detection coupled to mass spectrometry. Identity was confirmed by mass spectral match. The full certificate is published on this page, and every figure shown here is taken from it.

How much CJC-1295 without DAC is in the vial?

The laboratory measured 2.04 mg against a 2 mg label claim, which is 101.9% of label. Net content is reported on a per-vial basis. Astramide publishes the measured figure rather than the label claim, whether it falls above or below.

Was this CJC-1295 without DAC batch tested for endotoxins?

No endotoxin result appears on the certificate for this batch, so the row is shown as not reported rather than as a pass. Astramide does not display a result the laboratory did not produce.

How should this material be stored for research use?

As supplied, the lyophilized powder should be held at -20°C and protected from light and moisture. Once reconstituted, store at 2-8°C and use within 14 to 30 days. Avoid repeated freeze-thaw cycles and follow the handling procedures appropriate to your laboratory.

What is the difference between research-grade and pharmaceutical-grade CJC-1295 without DAC?

These are separate classifications. Research-grade material is supplied for laboratory research use only and is not intended for human or animal consumption. Pharmaceutical-grade is an FDA classification that applies to drugs manufactured for human use. Astramide supplies research-grade material only.

Why does this certificate show no lot number?

The laboratory issued this certificate with the Batch/Lot field left blank. Astramide identifies the lot by its white vial cap, lot White Cap. The certificate can still be verified against Krause Analytical laboratory reference 200510.

Research use only

This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.

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