| Pcs | Single Vial, 3-Pack, 6-Pack, Pack of 10 |
|---|---|
| Strength | 5mg |
CJC-1295 (without DAC)
Price range: $41.00 through $360.00
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VERIFICATION
How to read this report
CJC-1295 (without DAC), in structural terms.
- Sequence
- Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ One-letter shorthand: Y-D-A-A-I-F-T-Q-S-Y-R-K-V-L-A-Q-L-S-A-R-K-L-L-Q-D-I-L-S-R-NH₂ A commercial peptide reference lists this sequence for CJC-1295 without DAC.
- Molecular formula
- C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular weight
- Approximately 3367.9 g/mol
- CAS number
- 863288-34-0 — COA-reported This is the CAS number reported by Krause Analytical for the actual tested CJC-1295 No DAC sample.
- Structure type
- Linear peptide
- Primary molecular target
- Growth Hormone-Releasing Hormone Receptor (GHRHR) Unlike CJC-1295 with DAC, there is no albumin-binding DAC target interaction associated with this form.
- Physical form
- Lyophilized powder
- PubChem CID
- 91976842
CJC-1295 without DAC is a 29-amino-acid modified GHRH-derived peptide lacking the Drug Affinity Complex present in long-acting CJC-1295. Its structure incorporates substitutions intended to improve stability relative to native GHRH while preserving activity at the growth hormone-releasing hormone receptor.PubChem reports this molecular formula for CJC-1295 without DAC. The molecular weight is consistent with commercial structural records for CJC-1295 without DAC / Modified GRF (1-29).
Where CJC-1295 (without DAC) appears in the literature.
- GHRH receptor signaling studies
- Growth hormone secretion pathway research
- Pituitary-cell biology
- Somatotroph signaling studies
- GH/IGF-1 axis research
- Peptide stability research
- GHRH analog structure-function studies
- Comparative DAC versus non-DAC research
- Relevant experimental systems include:
- GHRH receptor-expressing cell systems
- Pituitary cell models
- Somatotroph-associated experimental systems
- GH secretion assays
- Endocrine signaling models
- Modified GHRH biochemical systems
- Peptide receptor-binding models
- HPLC-UV chromatographic purity analysis
- LC-MS identity confirmation
- Mass-spectrum/reference-spectrum matching
- GHRH receptor activation assays
- GH secretion assays
- Receptor-binding assays
- cAMP signaling assays
- Pituitary-cell response assays
- Chromatographic purity
- Peptide identity
- Peptide content
- GHRHR activation
- Intracellular cAMP signaling
- Growth hormone release
- Pituitary-cell response
- Peptide stability
What has been studied, and in what systems.
CJC-1295 (without DAC) is investigated primarily as a GHRH analog for experimental study of the growth hormone-releasing hormone receptor and downstream endocrine signaling.
Research areas include:
GHRH receptor signaling
Growth hormone secretion pathways
IGF-1-associated signaling
Pituitary biology
Somatotroph signaling
Endocrine pathway research
GHRH analog structure-function studies
Peptide pharmacology
Modified GRF research
Growth hormone pulse signaling
The non-DAC form is structurally related to Modified GRF (1-29), a stabilized GHRH-derived peptide designed to retain GHRH receptor activity while avoiding the albumin-binding DAC modification.
This distinction is important because much of the published human literature on CJC-1295 specifically concerns the DAC-containing long-acting form, not necessarily the non-DAC peptide. Published CJC-1295 studies therefore should not automatically be used to make pharmacokinetic claims about CJC-1295 without DAC.
These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.
Teichman SL et al., 2006. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. PMID 16352683. https://pubmed.ncbi.nlm.nih.gov/16352683/
Sackmann-Sala L et al., 2009. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. PMID 19386527. https://pubmed.ncbi.nlm.nih.gov/19386527/
Memdouh S et al., 2021. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Test Anal. PMID 34665524. https://pubmed.ncbi.nlm.nih.gov/34665524/
About this compound and its batch data.
What purity did this CJC-1295 without DAC batch achieve?
This lot was analysed by Krause Analytical and returned chromatographic purity of 99.31% by HPLC with UV detection coupled to mass spectrometry. Identity was confirmed by mass spectral match. The full certificate is published on this page, and every figure shown here is taken from it.
How much CJC-1295 without DAC is in the vial?
The laboratory measured 2.04 mg against a 2 mg label claim, which is 101.9% of label. Net content is reported on a per-vial basis. Astramide publishes the measured figure rather than the label claim, whether it falls above or below.
Was this CJC-1295 without DAC batch tested for endotoxins?
No endotoxin result appears on the certificate for this batch, so the row is shown as not reported rather than as a pass. Astramide does not display a result the laboratory did not produce.
How should this material be stored for research use?
As supplied, the lyophilized powder should be held at -20°C and protected from light and moisture. Once reconstituted, store at 2-8°C and use within 14 to 30 days. Avoid repeated freeze-thaw cycles and follow the handling procedures appropriate to your laboratory.
What is the difference between research-grade and pharmaceutical-grade CJC-1295 without DAC?
These are separate classifications. Research-grade material is supplied for laboratory research use only and is not intended for human or animal consumption. Pharmaceutical-grade is an FDA classification that applies to drugs manufactured for human use. Astramide supplies research-grade material only.
Why does this certificate show no lot number?
The laboratory issued this certificate with the Batch/Lot field left blank. Astramide identifies the lot by its white vial cap, lot White Cap. The certificate can still be verified against Krause Analytical laboratory reference 200510.
This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.






