Lot 2026/02 · Krause Analytical · reported 13 May 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterionAbove criterionNot on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
HPLC-UV-MS
Mass spectral match to the labelled compound
Confirmed
WITHIN SPEC
Chromatographic purity
HPLC-UV/MS
at or above 98.0%
>99.9 %
95at or above 98.0%100
WITHIN SPEC
Net content
HPLC-UV-MS
9.80 mg
80120
REPORTED
Endotoxin
LAL, USP <85>
below 0.5 EU/mL
<0.5 EU/mL
WITHIN SPEC
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Krause Analytical · 3 pages · served inline, not a screenshot
Quick reference
How to read this report
Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile
Ipamorelin, in structural terms.
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Molecular formula
C₃₈H₄₉N₉O₅
Molecular weight
Approximately 711.9 g/mol
CAS number
170851-70-4
Peptide length
5 amino acids
Structure type
Linear peptide
Parent sequence
Derived from GHRP-1 by removing its central Ala-Trp dipeptide (Raun et al., 1998); not a fragment of a natural protein
Primary molecular target
Growth hormone secretagogue receptor type 1a (GHS-R1a), also called the ghrelin receptor. Pharmacological profiling with GHRP and GHRH antagonists showed that ipamorelin acts through this GHRP-type receptor, not the GHRH receptor (Raun et al., 1998).
Ipamorelin is a synthetic linear pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH₂, with a C-terminal lysinamide. It contains three non-standard residues: α-aminoisobutyric acid (Aib), D-2-naphthylalanine and D-phenylalanine. It was identified within a series of compounds derived from GHRP-1 by removing that peptide's central Ala-Trp dipeptide. Its formula is C₃₈H₄₉N₉O₅ and its molecular weight is about 711.9 g/mol.
The growth hormone secretagogue receptor was cloned from pituitary and hypothalamus in 1996 as the target of synthetic GH-releasing peptides (Howard et al., 1996). Its endogenous ligand, ghrelin, was identified three years later as an acylated peptide from the stomach (Kojima et al., 1999).
Ipamorelin came out of a chemistry programme built on GHRP-1. In primary rat pituitary cells it released growth hormone with potency and efficacy similar to GHRP-6, and antagonist profiling showed it acts through a GHRP-type receptor (Raun et al., 1998).
The same study examined selectivity in swine. GHRP-6 and GHRP-2 raised ACTH and cortisol, but ipamorelin did not, even at doses more than 200-fold above its ED50 for GH release, and none of the compounds changed FSH, LH, prolactin or TSH (Raun et al., 1998). This selectivity is why ipamorelin is used as a reference compound in ghrelin receptor and pituitary research.
These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.
Cited literature
Raun K, Hansen BS, Johansen NL, Thøgersen H, et al., 1998. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. PMID 9849822. https://pubmed.ncbi.nlm.nih.gov/9849822/
Howard AD, Feighner SD, Cully DF, Arena JP, et al., 1996. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. PMID 8688086. https://pubmed.ncbi.nlm.nih.gov/8688086/
Kojima M, Hosoda H, Date Y, Nakazato M, et al., 1999. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. PMID 10604470. https://pubmed.ncbi.nlm.nih.gov/10604470/
Evidence level
Ipamorelin's receptor pathway and selectivity profile are established in cell-culture and animal-model studies, and the receptor and its endogenous ligand are well characterized. Statements on this page describe experimental systems, not outcomes in humans.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Lot 2026/02 was analysed by Krause Analytical and returned chromatographic purity of >99.9% by HPLC with UV detection coupled to mass spectrometry. Identity was confirmed by mass spectral match. The full certificate is published on this page, and every figure shown here is taken from it.
How much Ipamorelin is in the vial?
The laboratory measured 9.80 mg against a 10 mg label claim, which is 98.0% of label. Net content is reported on a per-vial basis. Astramide publishes the measured figure rather than the label claim, whether it falls above or below.
Was this Ipamorelin batch tested for endotoxins?
Yes. Endotoxin testing was performed using the Limulus Amebocyte Lysate assay in accordance with USP <85>, and this batch returned <0.5 EU/mL. The result appears on the certificate published on this page.
How should Ipamorelin be stored for research use?
As supplied, the lyophilized powder should be held at -20°C and protected from light and moisture. Once reconstituted, store at 2-8°C and use within 14 to 30 days. Avoid repeated freeze-thaw cycles and follow the handling procedures appropriate to your laboratory.
What is the difference between research-grade and pharmaceutical-grade Ipamorelin?
These are separate classifications. Research-grade material is supplied for laboratory research use only and is not intended for human or animal consumption. Pharmaceutical-grade is an FDA classification that applies to drugs manufactured for human use. Astramide supplies research-grade material only.
How can I verify this Ipamorelin certificate independently?
The certificate was issued by Krause Analytical under lot 2026/02, laboratory reference 205077. Quote that reference to the laboratory directly. The same document is published here in full, and is not summarised or reformatted by Astramide.
Research use only
This product is intended strictly for in-vitro laboratory research conducted by qualified professionals.
It is not intended for human or animal consumption, clinical use, or therapeutic application.
The statements on this page have not been reviewed by the FDA. These research peptides are not intended
to diagnose, treat, cure, or prevent any disease. Research Use Only.
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Know what's in it before you order.
Every Astramide batch is tested by an independent US lab. The report goes public before the batch goes on sale, so you can check the numbers first.
Independent US lab test on every batch
Full report published before it goes on sale
Kept frozen, shipped from Austin, Texas
GLP-3RLot 2026/02 · May 8, 2026
>99.9%purity by HPLC-UV/MS
90%Minimum 98.0%100%
Identity: Confirmed by mass specEndotoxin: Below 0.5 EU/mL
Pro Series
