Lot GND5 · 5 mg vial · Freedom Diagnostics · reported 9 June 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterionAbove criterionNot on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
LC-MS
LC-MS match to the labelled compound
Confirmed
WITHIN SPEC
Chromatographic purity
HPLC-UV
at or above 98.0%
99.94%
95at or above 98.0%100
WITHIN SPEC
Net content
HPLC-UV
5.84 mg
80120
REPORTED
Endotoxin
LAL, USP <85>
below the 0.05 EU/mL assay sensitivity
Pass, 2 of 2 at ≤0.05 EU/mL
WITHIN SPEC
Appearance
Visual
white lyophilized powder
White Lyophilized Powder
WITHIN SPEC
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Freedom Diagnostics · 1 page · served inline, not a screenshot
Quick reference
How to read this report
Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile
Gonadorelin Acetate, in structural terms.
Sequence
pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂
One-letter-style representation:
pE-H-W-S-Y-G-L-R-P-G-NH₂
This is the native mammalian GnRH decapeptide sequence; FDA documentation notes that gonadorelin has the same amino-acid sequence as the natural hormone.
Molecular formula
C₅₅H₇₅N₁₇O₁₃
Molecular weight
Approximately 1182.3 g/mol
CAS number
33515-09-2 — Gonadorelin The FDA substance database identifies this as the primary CAS for gonadorelin.
Peptide length
10 amino acids
Structure type
Linear peptide
Primary molecular target
Gonadotropin-Releasing Hormone Receptor (GnRHR / GnRH1R) GnRHR is the principal receptor through which GnRH regulates anterior pituitary gonadotroph signaling and gonadotropin secretion.
Gonadorelin is a synthetic decapeptide structurally identical to endogenous gonadotropin-releasing hormone (GnRH). It consists of ten amino-acid residues with an N-terminal pyroglutamyl residue and an amidated C-terminus. This compact peptide structure functions as the endogenous ligand framework for the GnRH receptor and serves as a reference molecule for studying GnRH receptor signaling and modified GnRH analogs.Formula and molecular weight are for gonadorelin base. The marketed material is named Gonadorelin Acetate; the certificate does not state acetate stoichiometry, so no fixed acetate formula is published here.
Research profile
Where Gonadorelin Acetate appears in the literature.
Gonadorelin is the synthetic form of endogenous GnRH and functions as an agonist of the gonadotropin-releasing hormone receptor.
GnRH receptor activation on anterior pituitary gonadotroph cells initiates intracellular signaling associated with synthesis and secretion of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
The biological response to GnRH is strongly influenced by the temporal pattern of receptor stimulation, making Gonadorelin particularly relevant to experimental research involving pulsatile endocrine signaling, receptor desensitization, and hypothalamic-pituitary communication.
Because Gonadorelin reproduces the endogenous GnRH peptide sequence, it should be distinguished from structurally modified, longer-acting GnRH agonists whose substitutions can substantially alter receptor affinity, degradation resistance, and pharmacology. Research comparing GnRH and modified analogs demonstrates that peptide substitutions can materially alter receptor-binding affinity.
These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.
Cited literature
Flanagan CA et al., 1998. A high affinity gonadotropin-releasing hormone (GnRH) tracer, radioiodinated at position 6, facilitates analysis of mutant GnRH receptors. Endocrinology. PMID 9751490. https://pubmed.ncbi.nlm.nih.gov/9751490/
Loumaye E et al., 1982. Binding affinity and biological activity of gonadotropin releasing hormone agonists in isolated pituitary cells. Endocrinology. PMID 6286282. https://pubmed.ncbi.nlm.nih.gov/6286282/
Evidence level
Extensive published literature Gonadorelin's sequence is identical to endogenous mammalian GnRH, and the molecule appears widely in the published endocrinology literature, predominantly in receptor-binding, cellular and animal-model studies. Astramide supplies this material for laboratory research use only.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions
About this compound and its batch data.
What is gonadorelin acetate?
Gonadorelin is a decapeptide, ten amino acids in length, structurally identical to endogenous gonadotropin-releasing hormone. Astramide supplies the acetate salt form as a lyophilized powder for laboratory research use only. It is not intended for human or animal consumption, clinical use, or therapeutic application.
Is gonadorelin the same as GnRH?
Gonadorelin is the synthetic form of gonadotropin-releasing hormone, also written GnRH or LHRH in the literature. The three names refer to the same decapeptide sequence. The acetate designation refers to the salt form the peptide is supplied in, not to a different molecule.
What purity does the current gonadorelin lot reach?
Lot GND5 returned 99.94% chromatographic purity, tested by Freedom Diagnostics under accession 2606080472. Identity was confirmed by LC-MS match to the labelled compound. The full Certificate of Analysis is published on the lot record and is downloadable as the laboratory’s own PDF.
How much gonadorelin is in the vial?
The label claim is 5 mg. Lot GND5 measured 5.84 mg, above label claim. Astramide publishes the measured figure for every lot, whether it sits above or below the claim, and the release criterion is at or above label claim.
How is Astramide's gonadorelin tested?
Lot GND5 was analysed by five methods at Freedom Diagnostics: identity by LC-MS, chromatographic purity, net content, endotoxin, and visual appearance. Endotoxin passed 2 of 2 replicates at or below 0.05 EU/mL. Appearance was reported as white lyophilized powder. Heavy metals, microbial and pH were not performed on this lot, and the report says so.
How should gonadorelin acetate be stored for research use?
Lyophilized material is stored at -20C and protected from light. Once reconstituted, storage is 2 to 8C with use within 14 to 30 days. Results from this lot apply to material handled within these conditions.
What is the difference between research-grade and pharmaceutical-grade gonadorelin?
These are separate classifications. Research-grade material is supplied for laboratory research use only and is not manufactured, tested or released under the regulatory framework that governs drugs for human use. Pharmaceutical-grade is an FDA classification for human-use products. Astramide supplies research-grade material exclusively.
Research use only
This product is intended strictly for in-vitro laboratory research conducted by qualified professionals.
It is not intended for human or animal consumption, clinical use, or therapeutic application.
The statements on this page have not been reviewed by the FDA. These research peptides are not intended
to diagnose, treat, cure, or prevent any disease. Research Use Only.
Get It Now
This product has multiple variants. The options may be chosen on the product page
Added to your cart
Your cart is empty.
Your Privacy Choices
We use analytics and advertising tools to understand how visitors find us and which campaigns work. You can turn either off. Your choice is saved in this browser.
AnalyticsGoogle Analytics, Microsoft Clarity and order source tracking. Helps us see how the site is used and fix problems.
Off (browser signal)
AdvertisingMeta and X pixels, and server-side events. Opting out also opts you out of "sharing" and targeted advertising under state privacy laws.
Off (browser signal)
Your browser is sending a Global Privacy Control signal, so analytics and advertising are off. To change this, turn off the signal in your browser settings.
Strictly necessary cookies (cart, sign-in, checkout, entry acknowledgment) always stay on. See our Privacy Policy.
Know what's in it before you order.
Every Astramide batch is tested by an independent US lab. The report goes public before the batch goes on sale, so you can check the numbers first.
Independent US lab test on every batch
Full report published before it goes on sale
Kept frozen, shipped from Austin, Texas
GLP-3RLot 2026/02 · May 8, 2026
>99.9%purity by HPLC-UV/MS
90%Minimum 98.0%100%
Identity: Confirmed by mass specEndotoxin: Below 0.5 EU/mL
Pro Series
Pro Series
Pro Series