Lot VP10 · 10 mg vial · Freedom Diagnostics · reported 9 June 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterionAbove criterionNot on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
LC-MS
LC-MS match to the labelled compound
Confirmed
WITHIN SPEC
Chromatographic purity
HPLC-UV
at or above 98.0%
99.28%
95at or above 98.0%100
WITHIN SPEC
Net content
HPLC-UV
9.63 mg
80120
REPORTED
Endotoxin
LAL, USP <85>
below the 0.05 EU/mL assay sensitivity
Pass, 2 of 2 at ≤0.05 EU/mL
WITHIN SPEC
Appearance
Visual
white lyophilized powder
White Lyophilized Powder
WITHIN SPEC
Values are reported per vial or bottle unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
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Quick reference
How to read this report
Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your product label. If they differ, this report is not for your product.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much compound is in each vial or bottle, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile
VIP (Vasoactive Intestinal Peptide), in structural terms.
Sequence
His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
One-letter representation:
HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH₂
VIP is a 28-residue C-terminally amidated peptide. The sequence corresponds to residues 125–152 of the human VIP precursor (UniProt P01282), from which VIP is released by post-translational processing.
Molecular formula
C₁₄₇H₂₃₇N₄₃O₄₄S
Molecular weight
3325.8 g/mol
CAS number
40077-57-4
Structure type
Linear peptide
Primary molecular target
VPAC1 and VPAC2 receptors (VIPR1 / VIPR2), class B G-protein-coupled receptors
In preclinical and laboratory research models, VIP has been investigated across numerous biological systems. Current research focuses include:
VPAC1 and VPAC2 receptor signaling
Cyclic AMP (cAMP) intracellular signaling pathways
Neuroendocrine communication
Immune cell signaling mechanisms
Pulmonary physiology
Gastrointestinal physiology
Smooth muscle signaling
Vascular biology
These observations are limited to controlled laboratory environments and support ongoing scientific investigation.
These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.
Cited literature
Langer I, 2012. Conformational switches in the VPAC(1) receptor. Br J Pharmacol. PMID 21806602. https://pubmed.ncbi.nlm.nih.gov/21806602/
Vomhof-DeKrey EE et al., 2008. TCR signaling and environment affect vasoactive intestinal peptide receptor-1 (VPAC-1) expression in primary mouse CD4 T cells. Brain Behav Immun. PMID 18534815. https://pubmed.ncbi.nlm.nih.gov/18534815/
Vomhof-DeKrey EE et al., 2008. Stimulatory and suppressive signal transduction regulates vasoactive intestinal peptide receptor-1 (VPAC-1) in primary mouse CD4 T cells. Brain Behav Immun. PMID 18555660. https://pubmed.ncbi.nlm.nih.gov/18555660/
Evidence level
Extensive published literature. VIP is an endogenous 28-residue neuropeptide and appears widely across the published receptor-pharmacology, immunology and gastrointestinal physiology literature, predominantly in biochemical, cellular and animal-model studies. This describes the evidence base surrounding the molecule and does not imply approval or established efficacy for the research material supplied here.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions
About this compound and its batch data.
What purity did this VIP batch achieve?
Lot VP10 was analysed by Freedom Diagnostics and returned chromatographic purity of 99.28% by HPLC with UV detection coupled to mass spectrometry. Identity was confirmed by mass spectral match. The full certificate is published on this page, and every figure shown here is taken from it.
How much VIP is in the vial?
The laboratory measured 9.63 mg against a 10 mg label claim. Net content is reported on a per-vial basis. Astramide publishes the measured figure rather than the label claim, whether it falls above or below.
Was this VIP batch tested for endotoxins?
Yes. Endotoxin testing was performed using the Limulus Amebocyte Lysate assay in accordance with USP <85>, and this batch returned a pass on both replicates at 0.05 EU/mL sensitivity. The result appears on the certificate published on this page.
How should VIP be stored for research use?
As supplied, the lyophilized powder should be held at -20°C and protected from light and moisture. Once reconstituted, store at 2-8°C and use within 14 to 30 days. Avoid repeated freeze-thaw cycles and follow the handling procedures appropriate to your laboratory.
What is the difference between research-grade and pharmaceutical-grade VIP?
These are separate classifications. Research-grade material is supplied for laboratory research use only and is not intended for human or animal consumption. Pharmaceutical-grade is an FDA classification that applies to drugs manufactured for human use. Astramide supplies research-grade material only.
How can I verify this VIP certificate independently?
The certificate was issued by Freedom Diagnostics under lot VP10, laboratory reference 2606080488. Quote that reference to the laboratory directly. The same document is published here in full, and is not summarised or reformatted by Astramide.
Research use only
This product is intended strictly for in-vitro laboratory research conducted by qualified professionals.
It is not intended for human or animal consumption, clinical use, or therapeutic application.
The statements on this page have not been reviewed by the FDA. These research peptides are not intended
to diagnose, treat, cure, or prevent any disease. Research Use Only.
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Know what's in it before you order.
Every Astramide batch is tested by an independent US lab. The report goes public before the batch goes on sale, so you can check the numbers first.
Independent US lab test on every batch
Full report published before it goes on sale
Kept frozen, shipped from Austin, Texas
GLP-3RLot 2026/02 · May 8, 2026
>99.9%purity by HPLC-UV/MS
90%Minimum 98.0%100%
Identity: Confirmed by mass specEndotoxin: Below 0.5 EU/mL
Pro Series
