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AOD-9604 Pro research peptide vial and box

AOD-9604 Pro

Pro Series
AOD-9604, a 16-residue analogue of the C-terminal region of human growth hormone
CAS 221231-10-3C₇₈H₁₂₃N₂₃O₂₃S₂Approximately 1815.1 g/mol16 amino acidsCyclic peptideLyophilized powder

Price range: $45.00 through $650.00

Ships from lot NHS-AOD05-20260828-01 · 5 mg vial · 99% purity · pH Solutions Lab See the COA
Why the Pro Series costs more
  • Synthesized in the USA. Domestic ground and air only, no ocean freight.
  • Released only above 99% HPLC purity.
  • Its own lot and its own published certificate.
How the Pro Series is made and tested
Ships from Austin, TexasUnited States only
Tested by an outside labNever in-house
Every lot publishedIncluding rejected lots
Same-day dispatchOn orders before 2pm ET
SKU: N/A Category: Tags: ,
BATCH
VERIFICATION
LOT NUMBER
NHS-AOD05-20260828-01
5 mg vial
IDENTITY
Match (C78H123N23O23S2, 1815.1 g/mol)
CHROMATOGRAPHIC PURITY
99%
NET CONTENT
5.0291 mg (100.582% of 5 mg label claim)
Analytical characterization

Every result against its specification.

Lot NHS-AOD05-20260828-01 · 5 mg vial · pH Solutions Lab · reported 29 September 2026 . The bar shows where the reported result falls against Astramide’s published release criterion. The notch marks the criterion.
Within criterion Above criterion Not on this COA
Test
Method
Criterion
Result
Result vs criterion
Status
Identity
Match to the labelled compound
Match (C78H123N23O23S2, 1815.1 g/mol)
WITHIN SPEC
Chromatographic purity
HPLC (210 nm)
at or above 99.0%
99%
95 at or above 99.0% 100
WITHIN SPEC
Net content
5.0291 mg (100.582% of 5 mg label claim)
80 120
REPORTED
Appearance
Visual
white lyophilized powder
White to off-white lyophilized powder cake, free of visible particulates
WITHIN SPEC
Water content
Karl Fischer
reported
0.0%
WITHIN SPEC
pH
reported
7.0
WITHIN SPEC
Water activity
within laboratory limit
0.2736 aw, pass
WITHIN SPEC
Microbial panel
not detected
Pass, 10 organisms and counts not detected
WITHIN SPEC
Heavy metals
within laboratory limits
Pass. As, Cd, Pb, Hg each 0.000 ppm
WITHIN SPEC
Residual solvents
within laboratory limits
Pass, 12 solvents each 0.000 ppm
WITHIN SPEC
Sterility
sterile
Pass
WITHIN SPEC
Mycotoxins
within laboratory limits
Pass
WITHIN SPEC
Endotoxin
LAL
—
Not reported on this certificate
NOT REPORTED
Values are reported per vial unless otherwise noted. Every figure here is taken from the batch Certificate of Analysis and nothing else.
Certificate of Analysis
AOD-9604 Pro · Lot NHS-AOD05-20260828-01 · 5 mg vial · Lab No. NHS-AOD05-20260828-01
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Quick reference

How to read this report

Same six keys on every Astramide product page. Only the values change.
1Lot numberMatch it to the number printed on your vial. If they differ, this report is not for your vial.
2IdentityMass spectrometry confirms the molecule is the one on the label. It conforms or it does not. There is no partial result.
3Chromatographic purityThe share of the material that is the target peptide. A purity figure quoted without a method is not a purity figure.
4Net contentHow much peptide is in the vial, as measured by the laboratory. A different question from purity.
5EndotoxinMeasured against a ceiling, not a floor. Sensitivity differs by laboratory, so results are not compared across labs.
6Laboratory, method, dateWho ran it, on what instrument, and when. A report with no named laboratory or no date is not a report.
Molecular profile

AOD-9604 Pro, in structural terms.

AOD-9604 Pro molecular structure
Sequence
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (YLRIVQCRSVEGSCGF), disulfide bridge Cys7-Cys14
Molecular formula
C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular weight
Approximately 1815.1 g/mol
CAS number
221231-10-3
Peptide length
16 amino acids
Structure type
Cyclic peptide
Parent sequence
Human growth hormone (somatotropin), residues 177-191, with an added N-terminal tyrosine
Primary molecular target
No single receptor target has been established in the analytical and structural literature cited on this page. The peptide corresponds to a C-terminal segment of growth hormone outside the main receptor-binding region of the intact protein.
Physical form
Lyophilized powder
PubChem CID
71300630

AOD-9604 is a synthetic 16-amino-acid peptide (YLRIVQCRSVEGSCGF). Residues 2 to 16 match residues 177 to 191 at the C-terminus of human growth hormone, and the N-terminal tyrosine is a synthetic addition, which is why it is often called hGH fragment 176-191. A disulfide bridge between the two cysteines (positions 7 and 14, Cys182 and Cys189 in the parent protein) closes a small ring.

Research profile

Where AOD-9604 Pro appears in the literature.

Peptide Chemistry; Analytical Chemistry; Structural Biology; Endocrinology
Research applications
  • Published studies have used AOD-9604 and the related hGH C-terminal fragment in:
  • Mass spectrometry detection and confirmation methods
  • In vitro metabolism and degradation product identification
  • NMR structural studies of the C-terminal disulfide loop
  • Peptide mapping and disulfide characterisation
Experimental systems
  • Biological matrices used for analytical method development
  • Liver microsome and enzymatic preparations for in vitro metabolism
  • Synthetic peptides in solution for NMR spectroscopy
Specific assays
  • LC-MS/MS quantification and metabolite identification
  • High-resolution mass spectrometry
  • Reversed-phase HPLC
  • Nuclear magnetic resonance spectroscopy
Measured endpoints
  • Analytical limits of detection and confirmation criteria
  • Metabolite identity and relative abundance
  • Solution conformation of the disulfide loop
  • Chromatographic purity and mass accuracy
Pcs

Single Vial, Pack of 10
Strength

5mg, 10mg
Mechanism and research context

What has been studied, and in what systems.

AOD-9604 is a modified C-terminal fragment of human growth hormone. Its sequence matches residues 177 to 191 of the hormone with an added N-terminal tyrosine, and it keeps the disulfide bridge that forms a small ring in that region of the parent protein.

Nuclear magnetic resonance studies of the corresponding growth hormone C-terminal fragment have described the conformation of this disulfide-bridged loop in solution (Strandberg et al., 1997).

Analytical research has developed mass spectrometry methods to detect AOD-9604 and has identified the products formed when it is broken down in vitro (Cox et al., 2015). These studies place AOD-9604 in peptide structure and analytical chemistry research.

These are published research systems. They do not describe approved clinical applications, and they do not establish efficacy or safety in humans.

Cited literature

Strandberg E et al., 1997. Nuclear magnetic resonance studies of the C-terminal human growth hormone fragment I179-C182-[SS]-C189-P191 and the related trisulfide peptide I179-C182-[SSS]-C189-P191. J Pept Res. PMID 9151258. https://pubmed.ncbi.nlm.nih.gov/9151258/
Cox HD et al., 2015. Detection and in vitro metabolism of AOD9604. Drug Test Anal. PMID 25208511. https://pubmed.ncbi.nlm.nih.gov/25208511/

Evidence level
The analytical and structural characterisation of AOD-9604 is documented in the published literature. Statements on this page describe experimental and analytical systems, not outcomes in humans.
Handling and storage
As supplied
Lyophilized powder in a sealed vial. Held in laboratory-rated freezers from arrival to shipment.
Storage
Store per the conditions printed on the vial label. Avoid heat, moisture and repeated temperature cycling.
Handling
For qualified professionals in controlled laboratory environments, following validated laboratory procedures.
Frequently asked questions

About this compound and its batch data.

What is AOD-9604?

AOD-9604 is a synthetic 16-amino-acid peptide (YLRIVQCRSVEGSCGF) based on the C-terminal region of human growth hormone, with a disulfide bridge forming a small ring. Its formula is C78H123N23O23S2, its molecular weight is about 1815.1 g/mol and its CAS number is 221231-10-3. AOD-9604 Pro is supplied as a lyophilized powder in a 5 mg vial. Sold for research use only.

What has AOD-9604 been examined for in published research?

Published analytical research has developed mass spectrometry methods to detect AOD-9604 and identified its in vitro breakdown products (Cox et al., 2015, PMID 25208511). Structural work has used NMR to describe the disulfide-bridged loop of the related growth hormone C-terminal fragment (Strandberg et al., 1997, PMID 9151258). Astramide makes no claim about outcomes in humans.

Is AOD-9604 the same as hGH fragment 176-191?

They are closely related names for the same research peptide. AOD-9604 matches residues 177 to 191 of human growth hormone with an extra tyrosine added at the N-terminus, which is why it is often listed as hGH fragment 176-191. It is a 16-residue peptide, much smaller than the 191-residue growth hormone protein it is derived from.

What purity does the current AOD-9604 Pro lot reach?

Lot NHS-AOD05-20260828-01 returned 99% chromatographic purity by HPLC at 210 nm, reported by pH Solutions Lab on 29 September 2026 under certificate 260901-899-NHS-4. Identity was confirmed as a match to AOD-9604 (C78H123N23O23S2, 1815.1 g/mol). The lot meets the Pro Series release criterion of at or above 99% HPLC purity. The full certificate is published on this page.

How much AOD-9604 is in the vial?

The label claim is 5 mg per vial. For lot NHS-AOD05-20260828-01, the laboratory measured 5.0291 mg of AOD-9604, which is 100.582% of the label claim. Astramide publishes the measured figure exactly as the laboratory reports it, above or below the label. Net content and chromatographic purity are separate measurements.

How should AOD-9604 be stored for research use?

Lyophilized AOD-9604 is stored at -20°C and protected from light. Once reconstituted, the solution is held at 2 to 8°C and used within 14 to 30 days. Repeated temperature cycling and exposure to moisture should be avoided, because both can affect peptide stability and the comparability of experimental results.

How is Astramide's AOD-9604 Pro tested?

Lot NHS-AOD05-20260828-01 was tested by pH Solutions Lab, an independent ISO/IEC 17025:2017 accredited laboratory (A2LA R243, PJLA Testing #84351). The certificate reports identity, chromatographic purity at 210 nm, net content, water content, pH, water activity, a 10-organism microbial panel, heavy metals, residual solvents, sterility and mycotoxins. Results apply only to this lot.

What does Pro Series mean for AOD-9604 Pro?

AOD-9604 Pro is part of the Astramide Pro Series. It is American-made, synthesized in the USA, and moves by domestic ground and air only, with no ocean freight. It is released under its own lot, and only when HPLC purity measures at or above 99%. The full certificate for each lot is published on this page.

Research use only

This product is intended strictly for in-vitro laboratory research conducted by qualified professionals. It is not intended for human or animal consumption, clinical use, or therapeutic application. The statements on this page have not been reviewed by the FDA. These research peptides are not intended to diagnose, treat, cure, or prevent any disease. Research Use Only.

COA library Every lot we have tested Search by batch number. Past lots stay published. How we test The analytical panel What each method measures and the criterion each lot must meet. Open Lab Send us your peptides Any vendor. Same lab. Your own Certificate of Analysis.
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Replacement or store creditOn approved claims. See refund policy.

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